One of the glories of our practice is the capacity to respond skillfully, with wisdom and compassion, to difficult, challenging, and/or painful experiences. In this talk and discussion, we explore six ways to practice skillfully with difficulties, focusing more in 1-5 on “inner" practices: (1) Stay connected with core teachings and perspectives, particularly about working with reactivity; (2) develop mindfulness in these situations, which helps us with non-reactivity and knowing what is happening; (3) have a few ways to come back to balance and non-reactivity after one is reactive, lost, stuck, or overwhelmed; (4) take the difficult situation as an opportunity to go more deeply, potentially uprooting some of the roots of reactivity and habitual tendencies; (5) continue to cultivate awakened qualities, helping us to shift our center of gravity from reactivity to responsiveness; and (6) cultivate ways of responding more skillfully in “outer” ways, including speech and interactions.