In the first part of the talk, we explore the Buddha's core teaching, "I teach dukkha and the end of dukkha." This teaching can be confusing as the Buddha gave at least four different meanings of "dukkha." We examine each of the four and find that only the last sense of dukkha as reactivity, developed in the teachings of the Two Arrows and Dependent Origination, makes sense of "the end of dukkha." We then look at ten ways of practicing with and transforming reactivity (see the attached file), discussing briefly each of the ten. The talk is followed by sharing, questions, and discussion.