We explore the topic of dealing with uncertainty. Although we never know what lies ahead, at this time the feeling of uncertainty is highlighted in a more acute way globally than ever before. What will happen next with the virus and its variants? Will people get vaccinated or will the anti-vax information continue to influence people's choices? What about climate disruption? Will we collectively wake up to the reality in time to keep from heading over the cliff of self-destruction? What does the Dharma offer us to wisely work with this unknown reality?